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For women with breast cancer

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Breast cancer is a very important health problem in the United States and various other countries around the world. Breast cancer occupies second rank as the leading cause of cancer deaths among women in America. Until recently cancer of the breast topped the list of leading causes of cancer deaths in women, it still occupies an unenviable second position, second only to lung cancer. If skin cancer is excluded, cancer of the breast is the commonest cancer among women living in America. According to the WHO, more than 1.2 million women get the new diagnosis of breast cancer every year in the world. These numbers represent tremendous challenges posed by breast cancer within the United States of America and across the world.

Breast cancer claims the top position as the leading cause of deaths from cancer among women aged between 40 and 55 years. Breast cancer can occur in males too; with about 1450 new cases of male breast cancer diagnosed every year in the United States. It is comforting to note that the deaths from breast cancer among women of all ages have declined in US by 2.8 percent for every year from 1990 to 2000. The declining mortality rates may be attributed to the successful screening programs and progress in various therapy modalities of breast cancer.


New way to predict breast cancer survival

New way to predict breast cancer survival
A team of scientists at the University of California, San Francisco has discovered a new way to predict breast cancer survival based on an "immune profile" � the relative levels of three types of immune cells within a tumor. Knowing a patient's profile may one day help guide therapy. Moreover, the UCSF team showed that they could use drugs to alter this immune profile in mice. Giving these drugs to mice, in combination with chemotherapy,........Go to the Main (Added on 4/3/2011 9:00:08 AM)


Certain breast cancer patients worry excessively

Certain breast cancer patients worry excessively
A newly released study has observed that certain types of women with early stage breast cancer are vulnerable to excessive worrying about cancer recurrence. Published early online in CANCER, a peer-evaluated journal of the American Cancer Society, the study also indicates that worrying about cancer recurrence can compromise patients' medical care and quality of life. Thanks to recent medical advances, most women who are diagnosed with early........Go to the Main (Added on 3/28/2011 7:07:53 AM)


Combining Targeted Agents To Treat Breast Cancer

Combining Targeted Agents To Treat Breast Cancer
A newly released study by Ohio State University cancer scientists provides a rational for treating breast cancer by combining two kinds of targeted agents, one that inhibits an overactive, cancer-causing pathway in cancer cells and one that reverses changes that silence genes that normally prevent cancer. Both types of agents are currently available and being reviewed individually in clinical trials, the scientists note. The findings,........Go to the Main (Added on 1/16/2011 9:25:26 PM)


Novel imaging technique may reduce lymphedema

Novel imaging technique may reduce lymphedema
ith guidance from a specialized scan, radiation oncologists at Mayo Clinic (http://www.mayoclinic.org/) were able to reduce by 55 percent the number of lymph nodes critical for removing fluid from the arm that received damaging radiation doses. The scientists report that integrating single photon emission computed tomography (SPECT) with the computerized tomography (CT) scans utilized for breast cancer radiotherapy planning may offer........Go to the Main (Added on 12/13/2010 7:22:59 AM)


Breast cancer patients prefer silicone

Breast cancer patients prefer silicone
A newly released study has observed that women who receive silicone implants after a double mastectomy are more satisfied with their breasts than women who receive saline implants. Published early online in CANCER, a peer-evaluated journal of the American Cancer Society, the findings may help physicians and breast cancer survivors as they together make decisions correlation to postmastectomy reconstructive surgery. Women who have one or both........Go to the Main (Added on 11/8/2010 7:34:55 AM)


Improved survival at every stage of breast cancer

Improved survival at every stage of breast cancer
Advances in screening for disease detection, better surgical techniques available to more women, and an increased number of therapies that reduce the risk of relapse in patients with both locally advanced and early stage disease, have collectively contributed to dramatic improvements in breast cancer's survival rates, as per a review of 60 years of patient records at The University of Texas MD Anderson Cancer Center. The single institution........Go to the Main (Added on 9/29/2010 11:01:54 PM)


Targeted breast radiation to control cancer

Targeted breast radiation to control cancer
A newly released study of patients with breast cancer at the Moores UCSD Cancer Center and the Arizona Oncology Services shows that after almost two years, the radiation given with the Strut-Adjusted Volume Implant (SAVI) controls the rate of cancer and may reduce the complications seen with alternate types of brachytherapy. This study also demonstrates the accuracy and flexibility of the device to maximize the dose to the target tissue and........Go to the Main (Added on 7/13/2010 7:04:23 AM)


Few women take tamoxifen to prevent breast cancer

Few women take tamoxifen to prevent breast cancer
Scientists with the National Cancer Institute (NCI) have observed that the prevalence of tamoxifen use for the prevention of breast cancer among women without a personal history of breast cancer is very low. Tamoxifen can reduce the risk of developing breast cancer in women who are at increased risk for developing the disease. Details of this survey are reported in the recent issue of Cancer Epidemiology, Biomarkers & Prevention, a journal........Go to the Main (Added on 2/8/2010 7:45:00 AM)


Mammography and breast cancer risk in some high-risk women

Mammography and breast cancer risk in some high-risk women
Low-dose radiation from annual mammography screening may increase breast cancer risk in women with genetic or familial predisposition to breast cancer, according to a study presented today at the annual meeting of the Radiological Society of North America (RSNA). "For women at high risk for breast cancer, screening is very important, but a careful approach should be taken when considering mammography for screening young women, particularly........Go to the Main (Added on 12/1/2009 8:28:36 AM)


Genes breast cancer risk

Genes breast cancer risk
Reporting this week in Nature Genetics, Wei Zheng, M.D., Ph.D, and his colleagues have identified a region on chromosome 6 that is strongly linked to breast cancer susceptibility in Asian women. This genetic "locus" may help guide efforts to find the specific genes linked with sporadic or non-inherited forms of the disease, the authors suggest. Breast cancer is one of the most common cancer types among women worldwide. Genetics plays an........Go to the Main (Added on 2/16/2009 10:21:56 PM)


Breast cancer and ostmenopausal hormone therapy

Breast cancer and ostmenopausal hormone therapy
Women who stopped taking the postmenopausal hormone combination of estrogen plus progestin experienced a marked decline in breast cancer risk which was uncorrelation to mammography utilization change, as per a research studyfrom the Women's Health Initiative led by a Los Angeles Biomedical Research Institute (LA BioMed) investigator that was published recently in The New England Journal (NEJM) "These findings support the hypothesis that the........Go to the Main (Added on 2/5/2009 6:25:34 AM)


Those women who need radiation

Those women who need radiation
ially lifesaving treatment, according to a new study from researchers at the University of Michigan Comprehensive Cancer Center. The study looked at 396 women who were treated with a mastectomy for breast cancer. The researchers found that 19 percent of women who fell clearly within guidelines recommending radiation treatment after the mastectomy........Go to the Main (Added on 2/4/2009 6:15:27 AM)


New compounds show promise for eliminating breast cancer tumors

New compounds show promise for eliminating breast cancer tumors
Two new compounds created by a University of Central Florida professor show early promise for destroying breast cancer tumors. Associate Professor James Turkson's compounds disrupt the formation and spread of breast cancer tumors in tests on mice. The compounds, S3I-201 and S3I-M2001, break up a cancer-causing protein called STAT3, and scientists have observed no negative side effects so far. "The compounds are very promising," Turkson........Go to the Main (Added on 11/19/2008 8:39:20 PM)


Improving treatment of inherited breast cancer

Improving treatment of inherited breast cancer
Researchers have identified some of the elusive downstream molecules that play a critical role in the development and progression of familial breast cancer. The research, published by Cell Press in the October 10th issue of the journal Molecular Cell, also identifies a compound found in grapes and red wine as an excellent candidate for therapy of some forms of breast cancer. About 8% of breast cancer cases are caused by mutations in tumor........Go to the Main (Added on 10/9/2008 10:54:16 PM)


Birth size is a marker of susceptibility to breast cancer

Birth size is a marker of susceptibility to breast cancer
Birth y published in PLoS Medicine by researchers at the London School of Hygiene and Tropical Medicine. Associations between birth size, perhaps as a marker of the pre-natal environment, and subsequent breast cancer risk have been identified before, but the findings from epidemiological studies have been inconsistent. ........Go to the Main (Added on 9/29/2008 10:43:53 PM)


Growth factor predicts poor outcome in breast cancer

Growth factor predicts poor outcome in breast cancer
The response to insulin-like growth factor 1 (IGF-I) in breast cancer cells predicts an aggressive tumor that is less likely to respond to therapy, said scientists at Baylor College of Medicine in a report that appears in the current issue of the Journal of Clinical Oncology. The finding gives impetus to the movement to tailor cancer therapys to attributes of the various tumors. "These findings come at a critical time," said Dr. Adrian Lee,........Go to the Main (Added on 8/31/2008 9:01:09 PM)


New Inhibitors Of Estrogen-dependent Breast Cancer Cells

New Inhibitors Of Estrogen-dependent Breast Cancer Cells
Scientists have discovered a new family of agents that inhibit the growth of estrogen-dependent breast cancer cells. The finding, described today at a meeting of the Endocrine Society, has opened an avenue of research into new drugs to combat estrogen-dependent breast cancers. "This cell-based study is exciting because it suggests these compounds are likely to be effective in tumors that remain dependent on estrogen for growth but are........Go to the Main (Added on 6/16/2008 9:57:48 PM)

Mammography may be beneficial to all women

Mammography may be beneficial to all women
According to researchers at The University of Texas M. D. Anderson Cancer Center, mammography, the gold-standard for breast cancer screening and early detection, has shown to significantly reduce the risk of being diagnosed with advanced stage breast cancer in women over the age of 80, an age group currently without clear guidelines recommending regular screenings. The study, published online today (April 21) in the Journal of Clinical........Go to the Main (Added on 4/21/2008 7:35:05 PM)

lapatinib shrinks breast cancer tumors in6 weeks

lapatinib shrinks breast cancer tumors in6 weeks
A drug that targets the cell surface receptors that play an important role in many types of cancer can bring about significant tumour regression in breast cancer after only six weeks of use, a scientist told the 6th European Breast Cancer Conference (EBCC-6). Dr. Angel Rodriguez, from the Lester and Sue Smith Breast Center, Baylor College of Medicine, Houston, USA, said that the work demonstrated for the first time that the tyrosine kinase........Go to the Main (Added on 4/17/2008 4:01:15 AM)

High levels of estrogen associated with breast cancer recurrence

High levels of estrogen associated with breast cancer recurrence
Women whose breast cancer came back after therapy had almost twice as much estrogen in their blood than did women who remained cancer-free despite therapy with anti-estrogen drugs in a majority of the women as per scientists as per a research findings reported in the recent issue of Cancer Epidemiology, Biomarkers and Prevention, a journal of the American Association for Cancer Research. The findings suggest that high levels of estrogen........Go to the Main (Added on 3/7/2008 5:34:31 AM)

Breast cancer diagnosis comes late

Breast cancer diagnosis comes late
Women who live in Chicago's gentrifying neighborhoods are more apt to receive a late diagnosis of breast cancer than women who live in poverty-stricken neighborhoods, University of Illinois at Chicago scientists have found. The surprising finding is as per a research findings reported in the recent issue of the Annals of Epidemiology. "There's been a lot of social change in American cities since 1990, but we know very little about how........Go to the Main (Added on 1/31/2008 11:01:21 PM)

Reducing Symptoms In Breast Cancer Patients

Reducing Symptoms In Breast Cancer Patients
Psychological interventions for cancer patients do more than just ease emotional distress - they directly improve health, new research suggests. A study of 227 patients with breast cancer observed that those who participated in a psychological intervention program were rated as having better health by a research nurse a full year after the program started. One especially important result was that patients who exercised received a higher........Go to the Main (Added on 1/28/2008 10:40:17 PM)

Choosing overly aggressive treatments for breast cancer

Choosing overly aggressive treatments for breast cancer
Despite a 1990 consensus recommendation from the National Institutes of Health (NIH) that lumpectomy plus radiation was the therapy of choice for early stage breast cancer, the United States continues to have the highest rate of mastectomy surgery among industrialized countries. Why would a person knowingly undertake a far more severe form of therapy when a lesser one would suffice? A recent survey shows that only 74 percent of women diagnosed........Go to the Main (Added on 1/8/2008 9:22:22 PM)

CT faster more accurate than mammography

CT faster more accurate than mammography
Cone-beam breast CT provides exceptional tissue contrast and can potentially reduce examination time with comparable radiation dose to conventional 2D mammography, as per a new study by a team of scientists from the University of Texas M. D. Anderson Cancer Center in Houston. Cone-beam breast CT employs a large area x-ray beam in conjunction with a flat panel x-ray detector to scan and generate 3D images of the breast. The scanner is placed........Go to the Main (Added on 12/28/2007 8:07:22 AM)

Stem cell transplant for breast cancer

Stem cell transplant for breast cancer
High-dose chemotherapy and autologous stem cell transplantation, the controversial, arduous, yet once-popular combination therapy that fell out of favor as a treatment for breast cancer, has proven not to be beneficial as an adjuvant treatment for women with node-positive disease, as per an expansive analysis conducted by scientists at The University of Texas M. D. Anderson Cancer Center. In a review of 15 randomized high-dose chemotherapy........Go to the Main (Added on 12/13/2007 9:58:59 PM)

Stereo Mammography Improves Cancer Detection

Stereo Mammography Improves Cancer Detection
A new radiological diagnostic tool called stereo mammography allows clinicians to detect more lesions and could significantly reduce the number of women who are recalled for additional tests following routine screening mammography. The findings from a clinical trial underway at Emory University were presented today at the annual meeting of the Radiological Society of North America held in Chicago. In the study, stereoscopic digital........Go to the Main (Added on 11/28/2007 10:02:46 PM)

Similarities In Dog, Human Breast Cancer

Similarities In Dog, Human Breast Cancer
Pre-cancerous mammary lesions in dogs and humans display a number of of the same characteristics, a discovery that could lead to better understanding of breast cancer progression and prevention for people and pets, said a Purdue University scientist from the School of Veterinary Medicine. A group of researchers including Sulma Mohammed have found similarities between non-malignant lesions that are considered to carry risk for developing........Go to the Main (Added on 11/15/2007 9:59:15 PM)

Extracts of catfish caught in polluted waters

Extracts of catfish caught in polluted waters
Exposing estrogen-sensitive breast cancer cells to extracts of channel catfish caught in areas with heavy sewer and industrial waste causes the cells to multiply, as per a University of Pittsburgh study being presented at the annual meeting of the American Public Health Association in Washington, D.C. The abstract, number 159141, will be presented at a special session on Contaminants in Freshwater Fish: Toxicity, Sources and Risk........Go to the Main (Added on 11/7/2007 8:59:34 PM)

 

A new breast cancer drug

A new breast cancer drug
A new drug targeting the PI3K gene in patients with advanced breast cancer shows promising results in an early phase I investigational study conducted at Virginia G. Piper Cancer at Scottsdale Healthcare, as per a presentation by oncologist Dr. Daniel D. Von Hoff at the 47th annual meeting of the American Society of Clinical Oncology (ASCO). The drug under investigation, GDC-0941, manufactured by Genentech Inc., South San Francisco, Calif.,........Go to the Main (Added on 7/20/2011 10:33:54 PM)


Reducing screening mammography errors

Reducing screening mammography errors
Radiologists who interpret a high volume of mammograms may not detect more cancers but are better at determining which suspicious lesions are not cancerous, as per a newly released study published online and in the April print edition of Radiology "Contrary to our expectations, we observed no clear association between volume and sensitivity," said the study's main author, Diana S.M. Buist, Ph.D., M.P.H., senior investigator at the Group........Go to the Main (Added on 2/22/2011 7:37:11 AM)


Protein related to aging holds breast cancer clues

Protein related to aging holds breast cancer clues
he most common type of breast cancer in older women � estrogen and progesterone receptor (ER/PR) positive breast cancer has been associated with a protein that fends off aging-related cellular damage. A newly released study led by Vanderbilt-Ingram Cancer Center researcher David Gius, M.D., Ph.D., now shows how a deficiency in this aging-associated protein may set the stage for these tumors to develop. The findings, published in........Go to the Main (Added on 1/28/2011 7:08:23 AM)


Breast cancer patients at risk for carpal tunnel syndrome

Breast cancer patients at risk for carpal tunnel syndrome
gene target for drug resistance, a triple-drug cocktail for triple negative breast cancer, and patients' risk for carpal tunnel syndrome are among study highlights scheduled to be presented by Johns Hopkins Kimmel Cancer Center researchers during the 33rd Annual CTRC-AACR San Antonio Breast Cancer Symposium, held Dec. 8-12. The information is embargoed for the time of presentation at the symposium. As a number of as half of postmenopausal........Go to the Main (Added on 12/13/2010 7:42:00 AM)


Breast-healthy lifestyle worthwhile

Breast-healthy lifestyle worthwhile
Having a family history of breast cancer can lead some people to wonder if their risk is out of their control. However, a study of more than 85,000 postmenopausal women found that regular physical activity, maintaining a healthy weight, and drinking less alcohol lowers breast cancer risk for women with, and without a family history of the disease. The University of Rochester Medical Center study, published online Oct. 12, 2010, by the........Go to the Facts (Added on 10/12/2010 7:22:32 AM)


Unusual drug-resistant breast cancer

Unusual drug-resistant breast cancer
Scientists at the University of Illinois at Chicago College of Medicine have found how gene expression that may contribute to drug resistance is ramped up in unusual types of breast tumors. Their findings may offer new treatment targets. The study is reported in the Oct. 8 issue of the Journal of Biological Chemistry, where it is designated a paper of the week. Approximately 70 percent of breast cancers express the estrogen receptor.........Go to the Main (Added on 10/11/2010 7:48:10 AM)


Risky nuclear breast imaging technologies

Risky nuclear breast imaging technologies
Some nuclear-based breast imaging exams may increase a woman's risk of developing radiation-induced cancer, as per a special report appearing online and in the recent issue of Radiology However, the radiation dose and risk from mammography are very low. "A single breast-specific gamma imaging (BSGI) or positron emission mammography (PEM) examination carries a lifetime risk of inducing fatal cancer greater than or comparable to a lifetime of........Go to the Main (Added on 8/24/2010 7:02:32 AM)


Radiation after mastectomy may not be needed for most

Radiation after mastectomy may not be needed for most
Patients with breast cancer with early stage disease that has spread to only one lymph node may not benefit from radiation after mastectomy, because of the low present-day risk of recurrence following modern surgery and systemic treatment, a finding that could one day change the course of therapy for thousands of women diagnosed each year, as per scientists at The University of Texas M. D. Anderson Cancer. The research, presented today in........Go to the Main (Added on 3/8/2010 9:33:00 AM)


Genes that cause resistance to breast cancer drugs

Genes that cause resistance to breast cancer drugs
Scientists at Dana-Farber Cancer Institute have discovered a gene activity signature that predicts a high risk of cancer recurrence in certain breast tumors that have been treated with usually used chemotherapy drugs. Despite their resistance to drugs of the anthracycline class, the breast cancers bearing this gene signature will probably still be vulnerable to other types of chemotherapy agents, say researchers in a letter to be published........Go to the Main (Added on 1/25/2010 8:01:36 AM)


Gene That Regulates Breast Cancer Metastasis

Gene That Regulates Breast Cancer Metastasis
Scientists at The Wistar Institute have identified a key gene (KLF17) involved in the spread of breast cancer throughout the body. They also demonstrated that expression of KLF17 together with another gene (Id1) known to regulate breast cancer metastasis accurately predicts whether the disease will spread to the lymph nodes. Previously, the function of KLF17 had been unknown. Deaths of most breast-cancer patients are the result of........Go to the Main (Added on 10/6/2009 7:51:29 AM)


Pregnancy has no impact on breast cancer

Pregnancy has no impact on breast cancer
A newly released study finds women who develop breast cancer while pregnant or soon afterwards do not experience any differences in disease severity or likelihood of survival in comparison to other women with breast cancer. The study is reported in the March 15, 2009 issue of CANCER, a peer-evaluated journal of the American Cancer Society. So-called pregnancy-associated breast cancers (PABC), defined as breast cancer that develops either........Go to the Main (Added on 2/9/2009 6:15:17 AM)


Digital Mammograms: Is it Efficient?

Digital Mammograms: Is it Efficient?
Digital mammograms take longer to interpret than film-screen mammograms, as per a research studyperformed at The University of Texas M.D. Anderson Cancer Center in Houston, Texas. The study included four radiologists who interpreted 268 digital screening mammograms and 189 film-screening mammograms. "The average interpretation time for all of our readers was 240 seconds (4 minutes) for digital screening mammograms and 127 seconds (2 minutes,........Go to the Main (Added on 1/6/2009 7:23:49 PM)


Preventing breast cancer with broccoli

Preventing breast cancer with broccoli
Women should go for the broccoli when the relish tray comes around during holiday celebrations this season. While it has been known for some time that eating cruciferous vegetables, such as broccoli, cauliflower, and cabbage, can help prevent breast cancer, the mechanism by which the active substances in these vegetables inhibit cell proliferation was unknown until now. Scientists in the UC Santa Barbara laboratories of Leslie Wilson,........Go to the Main (Added on 12/23/2008 10:36:53 PM)


Breast cancer common among women with family history

Breast cancer common among women with family history
New data presented at the American Association for Cancer Research's Seventh Annual International Frontiers in Cancer Prevention Research meeting outlines new data, which assesses breast cancer risk among women with a strong family history of breast cancer, but without a BRCA1 or BRCA2 mutation. This may facilitate earlier detection and prevention among high-risk women. The study, conducted at the University of Toronto, showed that women........Go to the Main (Added on 11/18/2008 5:25:32 AM)


3-week radiation therapy as effective as 5 weeks for breast cancer

3-week radiation therapy as effective as 5 weeks for breast cancer
Boston Early-stage patients with breast cancer who receive a more intensive course of radiation to their whole breast over three weeks is as effective as the standard, less intensive five-week whole breast radiation and offers patients more convenience at a lower cost, thereby providing a better quality of life, as per a randomized, long-term study presented September 22, 2008, in the plenary session at the American Society for Therapeutic........Go to the Main (Added on 9/22/2008 10:33:22 PM)


2 different breast cancer screening strategies are equally effective

2 different breast cancer screening strategies are equally effective
An organized population-based breast cancer screening program in Norway and an approach to screening that relies on physician- and self-referrals in Vermont are equally sensitive for detecting cancer, scientists report in the July 29 online issue of the Journal of the National Cancer Institute But the recall rate for abnormal mammograms was lower in Norway. Breast cancer screening in the United States is commonly initiated in response to a........Go to the Main (Added on 7/30/2008 12:10:08 AM)


Breast Cells Sets Stage For Abnormal Cell Division And Cancer

Breast Cells Sets Stage For Abnormal Cell Division And Cancer
A University of Michigan study reveals in detail how breast cells produce new cells that are predisposed to become malignant, unless they receive the protective action of the CHFR gene. CHFR expression is missing in more than a third of breast cancers. Analysis of this gene is also a hot area of interest among scientists trying to explain colorectal, stomach, lung and other forms of cancer. The new study reveals how and why new "daughter"........Go to the Main (Added on 6/19/2008 9:17:22 PM)

Switch regulates breast cancer response

Switch regulates breast cancer response
A tiny modification called methylation on estrogen receptors prolongs the life of these growth-driving molecules in breast cancer cells, as per research by researchers at Emory University's Winship Cancer Institute. The results are reported in the May 9, 2008 issue of the journal Molecular Cell. Most breast cancers contain estrogen receptors, which enable them to grow in the presence of the hormone estrogen. Their presence can determine........Go to the Main (Added on 5/8/2008 9:06:18 PM)

MRI 'best' for looking at breast cancer and more

MRI 'best' for looking at breast cancer and more
The use of MRI is effective in differentiating the blood supply to medial and lateral breast tumors, which is important in therapy planning and prognosis as per a research studyconducted by scientists at the University of Miami in Miami, FL and the Rabin Medical Center in Petah Tikva, Israel. Blood supply of medial tumors is mainly through the internal mammary vessels while lateral tumors may be supplied by both the internal or lateral........Go to the Main (Added on 4/13/2008 9:42:19 PM)

Gene Variant Increases Breast Cancer Risk

Gene Variant Increases Breast Cancer Risk
An international research consortium under the leadership of researchers of the German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) has shown that a common gene variant increases the risk of developing breast cancer. In roughly five to ten percent of breast cancer cases there is a family history of breast cancer- i.e., hereditary and, thus, genetic factors play a role here. Alterations in the genes known as BRCAI and........Go to the Main (Added on 3/16/2008 9:53:57 PM)

Test To reduce recurrence of breast cancer

Test To reduce recurrence of breast cancer
A new test that examines large sections of the sentinel lymph node for genes expressed by breast cancer could reduce the risk of recurrence and multiple surgeries, doctors say. The GeneSearch Breast Lymph Node Assay, manufactured by Veridex, L.L.C., a Johnson & Johnson company, is being used at the Medical College of Georgia to examine half of the tissue in the sentinel lymph node, the first place breast cancer typically spreads. The sample........Go to the Main (Added on 2/25/2008 9:18:06 PM)

NICE guidelines on breast cancer need urgent revision

NICE guidelines on breast cancer need urgent revision
The NICE guidelines on follow-up for patients with breast cancer need urgent revision, warn experts in this weeks BMJ. More than 1.2 million women and men worldwide are diagnosed with breast cancer each year and it is now recognised as a chronic disease that can recur even after 20 -30 years. Survival continues to improve, so new cancers are now more common in a number of patients than recurrence because the therapys of the first cancer........Go to the Main (Added on 1/17/2008 10:19:32 PM)

Taxol with avastin for metastatic breast cancer

Taxol with avastin for metastatic breast cancer
The positive results of the first nationwide clinical study showing the benefits of an antiangiogenic agent in breast cancer therapy are reported in the Dec. 27 issue of the New England Journal (NEJM). The study with Avastin showed the biggest improvement in metastatic breast cancer ever reported in a chemotherapy-based clinical trial. It nearly doubled the time between initiation of chemotherapy for metastatic disease and progression of the........Go to the Main (Added on 12/28/2007 8:14:50 AM)

Scientists identify and repress breast cancer stem cells

Scientists identify and repress breast cancer stem cells
By manipulating highly specific gene-regulating molecules called microRNAs, researchers at Cold Spring Harbor Laboratory (CSHL) report that they have succeeded in singling out and repressing stem-like cells in mouse breast tissue cells that are widely thought to give rise to cancer. If certain forms of breast cancer do indeed have their origin in wayward stem cells, as we believe to be the case, then it is critical to find ways to........Go to the Main (Added on 12/17/2007 8:45:40 PM)

Accuracy of diagnostic mammograms varies by radiologist

Accuracy of diagnostic mammograms varies by radiologist
For women with breast symptoms such as lumps, the ability of diagnostic mammograms to detect breast cancer accurately depends strongly on which radiologist reads them, as per a Group Health study published online on December 11 in the Journal of the National Cancer Institute. When a woman gets a mammogram, she wants to know that if she has breast cancer, the mammogram will be likely to detect it, said study leader Diana Miglioretti, PhD, an........Go to the Main (Added on 12/11/2007 10:40:44 PM)

BRCA1 mutations cause breast cancer

BRCA1 mutations cause breast cancer
An international team of scientists led by Columbia University Medical Centers Herbert Irving Comprehensive Cancer Center and Swedens Lund University has, for the first time, revealed how mutations in the BRCA1 gene lead to breast cancer. Findings show that one way BRCA1 mutations cause cancer is by knocking out a powerful tumor suppressor gene known as PTEN. The new study will be published online on the Nature Genetics website on Dec. 9,........Go to the Main (Added on 12/9/2007 5:17:51 PM)

Proteins As urvival Markers in Some Breast Cancers

Proteins As urvival Markers in Some Breast Cancers
New research suggests that the presence or absence of two proteins may be important markers for long-term survival in some breast-cancer patients. One of the proteins, called ErbB-4, is important for the growth and differentiation of several types of cells in the body. The second protein, called Wwox, is a tumor suppressor - it helps prevent cells from becoming malignant - and it is missing in a number of breast cancers. Researchers don't........Go to the Main (Added on 11/13/2007 9:39:42 PM)

Simpler way to assess breast cancer risk

Simpler way to assess breast cancer risk
A new, simpler model for predicting breast cancer risk in postmenopausal women appears to be as accurate as a more complicated method currently used to decide if women would benefit from medicine to reduce their risk of getting cancer, as per research published recently in the Journal of the National Cancer Institute. A team of scientists led by Rowan T. Chlebowski, a lead investigator at the Los Angeles Biomedical Research Institute at........Go to the Main (Added on 11/13/2007 9:24:39 PM)


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